Acute cryptosporidiosis as a cause of sudden recurrence of digestive symptoms in patients with Crohn's disease☆☆☆
Received 17 February 2010; received in revised form 20 May 2010; accepted 21 May 2010. published online 24 June 2010. Corrected Proof
Abstract
Gastrointestinal symptoms occurring in patients with Crohn's disease (CD) can be related to disease activity or to intercurrent infection. Absence of appropriate stool work-up can lead to misdiagnosis and wrong treatment. We report here two cases of acute cryptosporidiosis in patients with CD. This microorganism can trigger IBD flare or cause severe infections in immunocompromised host. Adding specific search for oocysts of Cryptosporidium parvum using the Ziehl–Neelsen technique to the microbiologic work-up from stools in patients with Crohn's disease seeking medical intervention for sudden exacerbation of digestive symptoms seems to be recommended.
aDepartment of Gastroenterology and Nutrition, AP-HP, Hôpital Saint-Antoine F-75012 and UPMC Univ Paris 06 F-75005, Paris, France
bDepartment of Parasitology, AP-HP, Hôpital Saint-Antoine F-75012 and UPMC Univ Paris 06 F-75005, Paris, France
Corresponding author. Université Paris VI, Department of Gastroenterology and Nutrition, Saint-Antoine Hospital, 184 rue du Faubourg Saint-Antoine 75571 PARIS Cedex 12, France. Tel.: +33 1 49 28 31 70; fax: +33 1 49 28 31 88.
☆ All authors have made substantial contributions to this manuscript.
☆☆ This manuscript is not under consideration elsewhere.
ABSTRACT
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